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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
34.55
Human Site:
Y196
Identified Species:
47.5
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
Y196
V
E
S
L
V
N
E
Y
D
D
N
G
E
G
I
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
Y176
V
E
S
L
V
N
E
Y
D
D
N
G
E
G
I
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
Y171
V
K
S
L
V
N
E
Y
D
D
N
G
E
G
I
Dog
Lupus familis
XP_535453
687
75990
Y378
V
E
S
L
V
N
K
Y
D
D
D
G
E
G
I
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
Y196
I
E
S
L
V
K
E
Y
D
D
N
G
E
G
I
Rat
Rattus norvegicus
P11598
505
56605
Y196
V
E
S
L
V
K
E
Y
D
D
N
G
E
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
Y173
Q
E
K
L
V
K
K
Y
E
P
D
G
E
G
I
Chicken
Gallus gallus
Q8JG64
505
56163
Y194
E
E
Q
L
V
Q
K
Y
E
E
D
G
E
G
V
Frog
Xenopus laevis
NP_001080051
502
56103
Y192
E
K
E
L
V
D
K
Y
D
T
N
G
E
G
V
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
Y188
D
V
G
A
G
L
K
Y
G
V
D
G
E
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A198
D
V
I
A
K
Y
E
A
K
D
N
G
V
V
L
Honey Bee
Apis mellifera
XP_623282
490
55838
E193
A
K
S
L
M
E
K
E
G
Y
K
N
T
I
V
Nematode Worm
Caenorhab. elegans
P34329
618
69779
W318
D
P
A
A
F
K
K
W
D
A
K
P
N
D
I
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
H187
D
S
G
L
A
E
K
H
S
G
T
D
K
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
G208
H
A
N
H
L
P
R
G
D
A
A
V
E
R
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
G203
D
A
K
F
L
P
R
G
E
S
V
E
G
P
A
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
K201
E
N
A
D
D
D
F
K
L
S
I
Y
L
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
93.3
N.A.
53.3
46.6
53.3
20
N.A.
26.6
13.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
73.3
80
80
40
N.A.
33.3
40
33.3
33.3
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
12
18
6
0
0
6
0
12
6
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
30
0
0
6
6
12
0
0
53
42
24
6
0
6
0
% D
% Glu:
18
42
6
0
0
12
36
6
18
6
0
6
65
0
0
% E
% Phe:
0
0
0
6
6
0
6
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
6
0
0
12
12
6
0
65
6
53
0
% G
% His:
6
0
0
6
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
6
0
6
0
0
0
0
0
0
0
6
0
0
6
48
% I
% Lys:
0
18
12
0
6
24
48
6
6
0
12
0
6
0
0
% K
% Leu:
0
0
0
65
12
6
0
0
6
0
0
0
6
0
6
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
6
0
0
24
0
0
0
0
42
6
6
0
0
% N
% Pro:
0
6
0
0
0
12
0
0
0
6
0
6
0
12
6
% P
% Gln:
6
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
0
0
6
0
% R
% Ser:
0
6
42
0
0
0
0
0
6
12
0
0
0
0
6
% S
% Thr:
0
0
0
0
0
0
0
0
0
6
6
0
6
0
0
% T
% Val:
30
12
0
0
53
0
0
0
0
6
6
6
6
12
30
% V
% Trp:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
6
0
59
0
6
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _